SLAS2017 Short Courses

Derivation, Maintenance, and Characterization Techniques for Human iPS Cells Used in Drug Discovery and Disease Modeling

This discussion based course will provide an overview on stem cell biology and the laboratory techniques used to derive and maintain human induced pluripotent stem cells (iPS). Additional topics will include the current state of stem cell research, manual and semi-automated reprogramming and maintenance techniques, and characterization assays and HTS strategies.

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David J. Kahler
NYU High Throuput Biology Core

David Kahler earned his Ph.D. in Molecular Medicine and Immunology from the Medical College of Georgia in the lab of Andrew Mellor. At the New York Stem Cell Foundation, Dr. Kahler served as the Director of the Flow Cytometry Core and Drug Discovery laboratories, and as Director of Laboratory Automation where he developed FCM/FACS based and automated technologies for the derivation, characterization and maintenance of human IPSC lines. Currently he is providing experimental design, assay development and data analysis support to clients of the High Throughput Biology Core Laboratory at the NYU Langone School of Medicine.

Kamal Garcha
GFY Biotech Consulting

Kamal Garcha earned his Ph.D. in the Department of Cellular and Physiological Sciences at the University of British Columbia where he developed a high content/throughput cell based assay to identify small molecules and pathways that influence chondrogenesis. As a post-doctoral fellow, he reprogrammed some of the first iPSCs from patients with bone and cartilage disorders in 2009, and later reprogrammed several lung tumor cell lines. This lead to Dr. Garcha's recruitment as a managing Director for the Canadian Centre for Commercialization of Regenerative Medicine's cell reprogramming and cell line engineering group. Currently, he is Sr. Project Manager at the University Health Network (Toronto), and provides consultative services to biotech and healthcare sectors.